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MHSalud

On-line version ISSN 1659-097X

Abstract

ARROYO-MOYA, Wilson; RODRIGUEZ-BUITRAGO, Alonso  and  BUITRAGO-ESPITIA, Jorge. Bibliometric analysis of research in genetic and anterior cruciate ligament rupture in sport: a review. MHSalud [online]. 2024, vol.21, n.1, pp.67-81. ISSN 1659-097X.  http://dx.doi.org/10.15359/mhs.21-1.16694.

Introduction:

Genetic component has been established as a significant risk factor for anterior cruciate ligament rupture (ACLR). Current research has focused on knowing the candidate genes that can influence and predispose a subject to this injury.

Objective:

A bibliometric analysis was carried out to trace the results of the research and identify global trends and gaps in knowledge about the relationship between the genetic component and ACLR.

Methodology:

Data were extracted from the Pubmed and Scopus databases and analyzed in the Bibliometrix package of the R software. A total of 63 studies published since 2007 were identified.

Results:

Most of the publications recovered were research articles (85.71%). The authors with the highest number of those are in Poland and South Africa. The analysis through the co-occurrence map reveals that there is a mainline of research based on the study of genetic polymorphisms, especially in the genes of the collagen families (COL1A1, COL5A1, COL12A1, in greater frequency). A total of 54 candidate genes were identified within the studies.

Conclusion:

We hope that this study can help to find key points and research gaps by providing a comprehensive analysis and structured information on this topic.

Keywords : genetic polymorphism; genes; anterior cruciate ligament; collagen.

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