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On-line version ISSN 1659-097X


ARROYO-MOYA, Wilson; RODRIGUEZ-BUITRAGO, Alonso  and  BUITRAGO-ESPITIA, Jorge. Bibliometric analysis of research in genetic and anterior cruciate ligament rupture in sport: a review. MHSalud [online]. 2024, vol.21, n.1, pp.67-81. ISSN 1659-097X.


Genetic component has been established as a significant risk factor for anterior cruciate ligament rupture (ACLR). Current research has focused on knowing the candidate genes that can influence and predispose a subject to this injury.


A bibliometric analysis was carried out to trace the results of the research and identify global trends and gaps in knowledge about the relationship between the genetic component and ACLR.


Data were extracted from the Pubmed and Scopus databases and analyzed in the Bibliometrix package of the R software. A total of 63 studies published since 2007 were identified.


Most of the publications recovered were research articles (85.71%). The authors with the highest number of those are in Poland and South Africa. The analysis through the co-occurrence map reveals that there is a mainline of research based on the study of genetic polymorphisms, especially in the genes of the collagen families (COL1A1, COL5A1, COL12A1, in greater frequency). A total of 54 candidate genes were identified within the studies.


We hope that this study can help to find key points and research gaps by providing a comprehensive analysis and structured information on this topic.

Keywords : genetic polymorphism; genes; anterior cruciate ligament; collagen.

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