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Medicina Legal de Costa Rica

On-line version ISSN 2215-5287Print version ISSN 1409-0015


PACHECO FIGUEROA, Carolina. Analysis of the effects of alcohol consumption in traumatic brain injury´s morbidity and mortality. Med. leg. Costa Rica [online]. 2020, vol.37, n.1, pp.39-44. ISSN 2215-5287.

Alcohol intoxication is often associated with traumatic brain injuries (TBIs), but the impact of alcohol on the pathogenesis and prognosis of TBIs remains unclear. Current literature provides evidence in terms of experimental and clinical data supporting alcohol’s neuroprotective effects in patients with TBIs.

To establish in a significative way this association, there lies a need for strong prospective observational studies, in order to comprehend the effects of alcohol on the long-term outcomes (including the neurological outcome) in patients with TBI with proper selection and baseline risk adjustment.

Keywords : Traumatic brain injury; Alcohol intoxication; Apoptosis; Caspase; neuroprotection; NMDA-receptor; Ethanol.

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