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Medicina Legal de Costa Rica

On-line version ISSN 2215-5287Print version ISSN 1409-0015


GONZALEZ RAMIREZ, Daniel; MADRIZ DE HAAN, Pedro  and  VILORIA GONZALEZ, Tibisay. Ductal carcinoma in situ of the breast with apocrine characteristics: case report. Med. leg. Costa Rica [online]. 2019, vol.36, n.1, pp.6-13. ISSN 2215-5287.

We present the case of a 69 year old female diagnosed with a ductal in situ carcinoma of the breast. The tumor had apocrine differentiation and a high nuclear grade. The clinical presentation corresponded to microcalcifications detected on mammography, which were histologically patent in the form of comedo type necrosis. The aforementioned apocrine differentiation was reassured using the aid of immunohistochemistry. The biopsy was an excisional biopsy, but due to positive quirurgical margins, the patient was later reintervened for total mastectomy.

Keywords : In situ ductal carcinoma; apocrine carcinoma; van Nuys scale; estrogen receptors; progesterone receptors; androgen receptors; GCDFP15.

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