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Medicina Legal de Costa Rica

On-line version ISSN 2215-5287Print version ISSN 1409-0015


VARGAS SANABRIA, Maikel; VEGA CHAVES, Juan Carlos; HERNANDEZ ROMERO, Gabriel  and  MONTERO SOLANO, Gustavo. Síndrome de brugada como casusa de muerte súbita de origen cardíaco. Med. leg. Costa Rica [online]. 2017, vol.34, n.1, pp.157-164. ISSN 2215-5287.

Sudden death is defined as an unexpected fatal event occurring in an apparently healthy subject. Sudden cardiac death is a leading cause, among which are primary electrical abnormalities such as Brugada Syndrome. Brugada Syndrome is an autosomal dominant channelopathy affecting the sodium channel. SCN5A has emerged as the most common gene associated with Brugada syndrome. The diagnosis is suggested by the clinical history in a patient with specific electrocardiographic pattern. The most typical presentation is syncope or resuscitated sudden death due to polymorphic ventricular tachycardia or ventricular fibrillation. An implantable cardioverter defibrillator is the main tool for preventing sudden death, and correct risk stratification in these patients is important both to prevent sudden death and to avoid unnecessary implantable cardioverter defibrillator use.

Keywords : Sudden cardiac death; Channelopathy; Brugada Syndrome; Ventricular tachyarrhythmia.

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