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Medicina Legal de Costa Rica

On-line version ISSN 2215-5287Print version ISSN 1409-0015


MADRIZ DE HAAN, Pedro  and  RODRIGUEZ, Greivin. Carcinoma de Merkel (carcinoma neuroendocrino). Med. leg. Costa Rica [online]. 2014, vol.31, n.2, pp.127-134. ISSN 2215-5287.

Since Merkel carcinoma was first described more than four decades ago by Cyril Toker little in the year 1972; has attracted interest from medical colleagues. Factors of this disease as their cell of origin, etiology, course and treatment today remain under discussion and change over time. The advent of electron microscopy and immunohistochemistry have collaborated in the etiological definition of this neoplasm and other discoveries such as the Merkel cell polyomavirus, have provided important information on the genesis of this process. The treatment of Merkel cell carcinoma is still suffering slight variations over time and remains in discussion to date. We report a patient with Merkel cell carcinoma with review of the current literature.

Keywords : Merkel cell carcinoma; dermatopathology; surgical pathology; Merkel cell; immunohistochemistry; electron microscopy.

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