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Medicina Legal de Costa Rica

On-line version ISSN 2215-5287Print version ISSN 1409-0015


CARVAJAL, Carlos. Lipoproteínas: metabolismo y lipoproteínas aterogénicas. Med. leg. Costa Rica [online]. 2014, vol.31, n.2, pp.88-94. ISSN 2215-5287.

Lipids travel in the blood in distinct particles containing both lipids and proteins called lipoproteins. There are four major classes of lipoproteins in blood: chylomicrons, VLDL, LDL and HDL. Chylomicrons transport triglycerides (TAG) to vital tissue (the heart, skeletal muscle and adipose tissue). The liver secretes VLDL, which serves to redistribute TAG for adipose tissue, heart and skeletal muscle. LDL transport cholesterol to cells and HDL removes cholesterol from cells to transport them to liver. TAG-rich lipoproteins and their remnants are atherogenic and are associated with other lipid risk factors (small and dense LDL particles and low HDL). LDL and Lp(a) are atherogenic particles. HDL is an anti-atherogenic lipoprotein.

Keywords : Lipoproteins; Triglyceride; Cholesterol and Apolipoproteins.

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