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Medicina Legal de Costa Rica

On-line version ISSN 2215-5287Print version ISSN 1409-0015


QUIROS ALPIZAR, José Luis  and  BARRANTES MONGE, Ricardo. Histiocitosis de células de langerhans en hueso parietal. Med. leg. Costa Rica [online]. 2012, vol.29, n.1, pp.97-101. ISSN 2215-5287.

The Langerhans Cell Histiocytosis is a group of diseases with a single or multisystem involvement, it´s clinic and complications vary depending on the tissue affected and the extent of the injury. The case of a 2 ½ years old female patient was presented, with a mass on the skull in the left parietal area of 22 days, 6-7 cm long, painful, deforms facial image and loss of appetite. The CT scan showed a fracture of the parietal bone, increase of homogeneous solid volume without calcification. The treatment was a tumor resection, craniotomy and cranioplasty, the histopathological study showed immunohistochemically cells S100, CD1a and CD68 positive

Keywords : Histiocytosis; eosinophilic granuloma; Histiocytosis X; Langerhans cell histiocytosis; Langerhans cells; lytic lesions; biopsy; immunohistochemistry; CD1a; S100; CD 68.

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