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Acta Médica Costarricense

On-line version ISSN 0001-6002Print version ISSN 0001-6012


LARA-FERNANDEZ, Gloria Esther et al. Ozone a method of disinfection of the environment of hospitals. Acta méd. costarric [online]. 2020, vol.62, n.2, pp.72-78. ISSN 0001-6002.

Background and aim:

Health care-associated infections raise costs, prolong hospital stays and increase mortality, making environmental disinfection necessary as a method of reducing this problem. The aim of this study was to evaluate the impact of the use of ozone for environmental disinfection in areas of high hospital risk.


An intervention was carried out to disinfect the environment with the use of ozone equipment in high-risk areas of the Cuban Institute of Neurology an Neurosurgery and the result was evaluated using the following variables: environmental microbiological status, number of deaths in general and for sepsis, and consumption of antibiotics from January to June 2019.


Of the 12 areas evaluated, prior to the application of ozone, taking into account the number of colony forming units per m3, 2 were classified as unacceptable, 3 as an acceptable environment and 7 as a clean environment . After the ozone application, the results of the 12 areas showed a very clean environment. Antibiotic use decreased to a third in the exposed areas evaluated and rose in the unexposed areas. There were fewer deaths than in a similar period of the year prior to the intervention.


Environmental disinfection with ozone in high-risk hospital areas is useful to generate clean environments, and favor the decrease in antibiotic consumption and mortality due to infections associated with healthcare.

Keywords : Disinfection; ozone; microbiology; in-hospital infections..

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