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Acta Médica Costarricense

On-line version ISSN 0001-6002Print version ISSN 0001-6012


JIMENEZ-MONTERO, José G.  and  CARTIN-CABALLERO, Victor. Severe neutropenia induced by propylthiuracil. Acta méd. costarric [online]. 2018, vol.60, n.1, pp.45-47. ISSN 0001-6002.

Patients with hyperthyroidism have several treatment options. The treatment of Graves’ disease consists of blocking the excess of thyroid hormones using thionamides, thyroidectomy or I131 therapy. Antithyroid agents such as methimazole, carbimazole, propylthiuracil are effective in controlling hyperthyroidism in patients with Graves’ disease, but they have adverse effects including, allergies, gastritis, hepatitis and agranulocytosis. We present a hyperthyroid patient with severe neutropenia during treatment with propylthiuracil.

Keywords : Graves disease; antithyroid drugs; propylthiuracil; hyperthyroidism; agranulocytosis.

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