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Acta Médica Costarricense

On-line version ISSN 0001-6002Print version ISSN 0001-6012


CASTRO-VOLIO, Isabel; ORTIZ-MORALES, Fernando  and  VALLE-BOURROUET, Luisa. Karyotypes in pregnancy losses, first 31 cases studied in Costa Rica. Acta méd. costarric [online]. 2013, vol.55, n.4, pp.188-191. ISSN 0001-6002.

The laboratory has received 31 samples of abortion material since 2005. For 24 cases, we have information about the gestational age at which the sample was taken. All cases were an early pregnancy loss except for one with 26 weeks of pregnancy. The average gestational age for cases of early abortion was 8 weeks and 6 days. All samples had some degree of bacterial contamination. However, out of 31 samples, we failed to obtain cell cultures only in 7 due to high contamination. Therefore, the failure rate of the cultures was 22%. Out of the 24 karyotypes obtained, 15 were 46, XX, 3 were 46, XY and 6 were abnormal, for a 25% of chromosome aberrations in these samples. It is possible that the percentage of abnormal chromosomes found is underestimated due to sample contamination with maternal cells. For 90% of cases, the average turn around time of the laboratory was 24 days.

Keywords : pregnancy loss; karyotypes; cytogenetics.

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