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Acta Médica Costarricense

On-line version ISSN 0001-6002Print version ISSN 0001-6012


ROJAS-BARAHONA, Roubier; ROMERO-ZUNIGA, Juan José  and  SALAZAR-SANCHEZ, Lizbeth. Asociación entre anticuerpos antifosfolípidos y complicaciones de la gestación en mujeres de Costa Rica. Acta méd. costarric [online]. 2007, vol.49, n.2, pp.102-106. ISSN 0001-6002.

Aim: To determine the association between antiphospholipid antibodies and pregnancy failures (abortion, preclampsia, eclampsia, placental insufficiency or delivery before the 34th week of gestation) in Costa Rican women. Materials and Methods: The present is a case-control study, the participants belong to the Obstetrics Department of the Hospital Mexico. The period of the study was from January 2002 to December 2004. The data was obtained from the discharge registry of the Hospital descriptive analysis was done followed by univariate and multivariate analysis of the main variables. Results: The age the patients did not show difference between cases and controls. San Jose reported a higher percentage of cases with 39.9%, followed by Heredia (26.8%) and Alajuela (24.6%). An association between the antiphospholipid antibodies and pregnancy failures in women in Costa Rica was found. The number of pregnancies did not affect the abortion and other pregnancy failures. With the unvaried and multivariate analyses a strong association between the history of the previous pregnancies was determined, and a high relationship between the antiphospholipid antibodies with abortion and other pregnancy failures was also found. Conclusion: The antiphospholipid antibodies should be taken into account during the follow-up of the pregnancy in patients with history of abortions or pregnancy failures.

Keywords : abortion; pregnancy failures; antiphospholipid antibodies; case-control study; Costa Rica.

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