Abstract

ALBURQUEQUE-MELGAREJO, Joseph; ROQUE-QUEZADA, Juan Carlos; DULANTO-MOSCOSO, Luis Javier  and  VIRU-FLORES, Horus Michael. Relapse of high grade follicular lymphoma in thyroid. Acta méd. costarric [online]. 2022, vol.64, n.3, pp.43-49. ISSN 0001-6002.

Follicular thyroid lymphoma is a rare entity that represents less than 2% of extranodal lymphomas; and whose main risk factor is Hashimoto's thyroiditis. This tends to affect older adult patients with greater predisposition, where it usually presents as a rapidly growing mass with compromise of the adjacent structures in the neck. However, given its rare incidence, this pathology should be suspected by the clinician for an early diagnosis. Although there are currently no standardized management guidelines for this entity, it usually responds well to radiotherapy and chemotherapy. The present case describes the history of a patient with a relapse of high-grade follicular-type NHL located in the thyroid who presented to the emergency room with dysphonia, bilateral paralysis of the vocal cords, change in tone of voice and dysphagia, with the history of high-grade follicular lymphoma in retroperitoneal location in remission after 8 cycles of chemotherapy with Rituximab, Cyclophosphamide, Doxorubicin, Vincristine and Prednisone, which presented cytoreduction after treatment with chemotherapy with the protocol Rituximab, Dexamethasone, Cytarabine and Cisplatin.

Keywords : Lymphoma; Thyroid Gland; Recurrence; Lymphome folliculaire; Aged; Chemotherapy.

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