Abstract

CHANG, Yai-Linn; OROZCO-SABORIO, Leonardo; AZOFEIFA-HERNANDEZ, Ileana  and  MONTIEL-LARIOS, Gerardo. Determination of fasting plasma glucose cut-off valuefor the identification of abnormal carbohydrate tolerance in women with polycystic ovarian syndrome. Acta méd. costarric [online]. 2012, vol.54, n.4, pp.246-251. ISSN 0001-6002.

Objective: To determine the predictive value of fasting glucose to identify abnormal carbohydrate tolerance in patients with polycystic ovary syndrome. Materials and methods: 100 women diagnosed with polycystic ovary syndrome underwent a tolerance test toa 75 gdose of glucose. Results: Sensitivity for a threshold value of 101 mg/dl was 41.7% (95% C.I.: 23% - 63%) and specificity 92.1% (95% C.I.: 83% - 97%); with a positive predictive value of 62.5% and a negative predictive value of 83.3%. The optimum cut-off value was 93 mg/dL, with a sensitivity of 75% (95% C.I.: 53% - 89%) and a specificity of 73.7% (95% C.I.: 62% - 83%). The optimum fasting plasma glucose cut-off value for intolerance in women with PCOS was 93md/dL. Conclusions: The current recommendations for diagnosing abnormal carbohydrate tolerance in women with polycystic ovary syndrome are not appropriate.

Keywords : abnormal carbohydrate tolerance; polycystic ovary syndrome; screening.

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