Abstract

RAMIREZ-CORRALES, José A.. Cirrhosis and hepatocarcinoma in HBV. Acta méd. costarric [online]. 2008, vol.50, suppl.3, pp.26-27. ISSN 0001-6002.

HBV cirrosis: The surface antigen can be detected by biopsy, orcein tinctions (emery hepatocytes), and immunohistochemistry (surface antigen and anticore). Evolution Stages: a) Early or incipient (non-defined nodes, a lot of fibrosis and architectural alteration); b) established (nods completely surrounded by fibrotic bands). Histological Stages: a) active (main necrosis and inflammation; and cholestasis); b) inactive (little necrosisor inflammation). Types of Hepatocarcinomas: trabecular-clear cells- adenoid-solid-scirrhous. The immunohistochemistry helps to define the type using the hepatocellular antigens, carcinoembryonic antigen, cytokeratin, chromogranins and synapto-physins.

Keywords : hepatocellular carcinoma; cirrhosis; hepatocellular dysplasia; hepatocarcinogenesis by hepatitis B virus; emery hepatocytes; immunohistochemistry.

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