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Odovtos International Journal of Dental Sciences

versão On-line ISSN 2215-3411versão impressa ISSN 1659-1046


GONZALEZ QUESADA, Jorge  e  RIVERA ALVAREZ, Sonia. Effect of Nonsurgical Periodontal Treatment on Levels of Pyridinoline (ICTP) in the Gingival Crevicular Fluid (GCF). Odovtos [online]. 2017, vol.19, n.1, pp.77-85. ISSN 2215-3411.

The destructive periodontal disease affects the tissues supporting the teeth, with the final result in the loss of it; so the research is directed towards identifying objective measures of risk such as biomarkers of destruction. Because studies of biomarkers present in the gingival crevicular fluid (FGC) have reported promising results, it is posible associated markers of tissue degradation with the progression of periodontal disease. The aim of this study is to determine the effect of nonsurgical periodontal treatment on the levels of pyridinoline in the FGC patients with chronic periodontitis. Materials and Methods: FGC samples (before and after treatment), both active and inactive sites determined by the method of tolerance, ICTP levels were measured using the ICTP EIA. Uni Q, the results were analyzed using Stata 7.0 program and the student-test for nonparametric samples Results: ICTP levels decreased significantly after performing non-surgical periodontal treatment (p = 0.0001). Conclusions: According to the results, the ICTP may be a good marker to monitor the effects of nonsurgical periodontal treatment.

Palavras-chave : Pyridinoline; Periodontitis; Gingival crevicular fluid.

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