<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2215-3411</journal-id>
<journal-title><![CDATA[Odovtos International Journal of Dental Sciences]]></journal-title>
<abbrev-journal-title><![CDATA[Odovtos]]></abbrev-journal-title>
<issn>2215-3411</issn>
<publisher>
<publisher-name><![CDATA[Facultad de Odontología. Universidad de Costa Rica]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2215-34112017000100077</article-id>
<article-id pub-id-type="doi">10.15517/ijds.v0i0.27465</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Efecto del tratamiento periodontal no quirúrgico sobre los niveles de Piridinolina (ICTP) en el fluido gingival crevicular (FGC)]]></article-title>
<article-title xml:lang="en"><![CDATA[Effect of Nonsurgical Periodontal Treatment on Levels of Pyridinoline (ICTP) in the Gingival Crevicular Fluid (GCF)]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[González Quesada]]></surname>
<given-names><![CDATA[Jorge]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rivera Alvarez]]></surname>
<given-names><![CDATA[Sonia]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de Costa Rica Sección de Periodoncia Facultad de Odontología]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>CR</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad de Chile Facultad de Odontología ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>CL</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>04</month>
<year>2017</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>04</month>
<year>2017</year>
</pub-date>
<volume>19</volume>
<numero>1</numero>
<fpage>77</fpage>
<lpage>85</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_arttext&amp;pid=S2215-34112017000100077&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_abstract&amp;pid=S2215-34112017000100077&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_pdf&amp;pid=S2215-34112017000100077&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[ResumenLa enfermedad periodontal destructiva afecta los tejidos de soporte del diente, teniendo como consecuencia final la pérdida del mismo; por lo cual la investigación se dirige hacia medidas objetivas de identificación de riesgo como lo son los biomarcadores de destrucción. Debido a que los estudios realizados con biomarcadores presentes en el fluido gingival crevicular (FGC) han reportado resultados promisorios, es factible asociar marcadores de degradación tisular con la progresión de la enfermedad periodontal. El objetivo del presente estudio es determinar el efecto del tratamiento periodontal no quirúrgico, sobre los niveles de ICTP en el FGC de pacientes con periodontitis crónica. Materiales y métodos: En muestras de FGC (pre y postratamiento), tanto de sitios activos como de inactivos determinados según el método de tolerancia, se midieron los niveles de ICTP utilizando el ICTP EIA. Uni Q, los resultados se analizaron usando el programa Stata 7.0 y el student-test para las muestras no paramétricas. Resultados: Los niveles de ICTP disminuyeron significativamente después de realizar el tratamiento periodontal no quirúrgico (p= 0,0001). Conclusiones: De acuerdo con los resultados obtenidos, la ICTP puede ser un buen marcador para monitorear los efectos del tratamiento periodontal no quirúrgico.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[AbstractThe destructive periodontal disease affects the tissues supporting the teeth, with the final result in the loss of it; so the research is directed towards identifying objective measures of risk such as biomarkers of destruction. Because studies of biomarkers present in the gingival crevicular fluid (FGC) have reported promising results, it is posible associated markers of tissue degradation with the progression of periodontal disease. The aim of this study is to determine the effect of nonsurgical periodontal treatment on the levels of pyridinoline in the FGC patients with chronic periodontitis. Materials and Methods: FGC samples (before and after treatment), both active and inactive sites determined by the method of tolerance, ICTP levels were measured using the ICTP EIA. Uni Q, the results were analyzed using Stata 7.0 program and the student-test for nonparametric samples Results: ICTP levels decreased significantly after performing non-surgical periodontal treatment (p = 0.0001). Conclusions: According to the results, the ICTP may be a good marker to monitor the effects of nonsurgical periodontal treatment.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Piridinolina]]></kwd>
<kwd lng="es"><![CDATA[Periodontitis]]></kwd>
<kwd lng="es"><![CDATA[Fluido gingival crevicular]]></kwd>
<kwd lng="en"><![CDATA[Pyridinoline]]></kwd>
<kwd lng="en"><![CDATA[Periodontitis]]></kwd>
<kwd lng="en"><![CDATA[Gingival crevicular fluid]]></kwd>
</kwd-group>
</article-meta>
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