1409-4142 1409-4142 S1409-41422014000200032 00 12 2014 00 12 2014 16 2 32 36 1948 32 925-48 2014 100 54-9 2009 72 37-40 1996 47 523-9 2012 80 253-6 2015 88 93-7 2008 48 918-85