<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2215-3411</journal-id>
<journal-title><![CDATA[Odovtos International Journal of Dental Sciences]]></journal-title>
<abbrev-journal-title><![CDATA[Odovtos]]></abbrev-journal-title>
<issn>2215-3411</issn>
<publisher>
<publisher-name><![CDATA[Facultad de Odontología. Universidad de Costa Rica]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2215-34112021000200171</article-id>
<article-id pub-id-type="doi">10.15517/ijds.2021.45383</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[¿Es la proteína C reactiva un indicador de riesgo periodontal?]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rojas-González]]></surname>
<given-names><![CDATA[Gisella]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Silva de la Fuente]]></surname>
<given-names><![CDATA[Sandra]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de Costa Rica Facultad de Odontología Sección de Periodoncia]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Costa Rica</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad de Costa Rica Facultad de Microbiología Centro de Investigación en Biología Celular y Molecular (CIBCM)]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Costa Rica</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>08</month>
<year>2021</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>08</month>
<year>2021</year>
</pub-date>
<volume>23</volume>
<numero>2</numero>
<fpage>171</fpage>
<lpage>180</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_arttext&amp;pid=S2215-34112021000200171&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_abstract&amp;pid=S2215-34112021000200171&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_pdf&amp;pid=S2215-34112021000200171&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN: La periodontitis es una enfermedad inflamatoria crónica, multifactorial, causada por microorganismos y caracterizada por la destrucción progresiva del tejido de soporte dental. En los últimos años se han realizado estudios que señalan cierta similitud y asociación entre la periodontitis y la enfermedad cardiovascular aterosclerótica. Esta relación se ha establecido por tener ciertos factores de riesgo en común y por producir incremento plasmático de la proteína C reactiva (P-CR). A esta proteína se le atribuyen características favorables como marcador inflamatorio. Este estudio busca establecer si existe algún tipo de relación, entre la periodontitis y los valores de la P-CR antes de iniciar el tratamiento periodontal, en un grupo de pacientes de la Facultad de Odontología de la Universidad de Costa Rica. Se hicieron exámenes periodontales a 30 pacientes y se obtuvo una muestra de sangre de cada uno para determinar la concentración de P-CR. Con respecto al valor de la P-CR, se encontró que el promedio fue de 3.72mg/L (IC95%: 2.06-5.38), lo que constituye un marcador de riesgo de moderado a severo. El 54% de los pacientes presentó enfermedad periodontal crónica generalizada, sin que se encontrara diferencia estadísticamente significativa por sexo (p=0.416), ni edad (p=0.477). El 43% de los pacientes padecía de enfermedad periodontal crónica localizada y el 3% de los pacientes presentaron gingivitis. Se observó que el género femenino mostró relativamente, un mayor riesgo cardiovascular respecto al género opuesto (p=0.640). No se encontró diferencia estadísticamente significativa en el valor de P-CR por sexo, edad o la presencia de otras enfermedades, aunque esta cifra fue mayor en los que presentaron enfermedades metabólicas (5.5mg/L) con respecto a quienes no las padecían (2.7mg/L).]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT: Periodontitis is an inflammatory multifactorial chronic disease, caused by microorganisms that destroys periodontal tissues. In the last years, several studies have described an association between periodontitis and atherosclerotic cardiovascular disease. This relationship has been made since both diseases share the same risk factors and they both increase C reactive proteins levels. C-reactive protein (C-RP) is a well-known inflammatory marker. This study was designed to try to stablish the relationship between C-RP levels and periodontitis in a group of patients that need periodontal treatment at Odontology Faculty in Universidad de Costa Rica. Periodontal examinations were done to 30 patients and blood samples were taken. The mean value of C-RP found was 3.72mg/L (IC95%: 2.06-5.38) which represents a medium- high risk level. 54% of the patients had generalized chronic periodontitis, without statistical difference when compared gender (p=0.416) or age (p=0.477). 43% had chronic localized periodontitis and 3% gingivitis. Females showed a higher risk for cardiovascular disease (p=0.640). No statistical differences were found between C-RP values relating gender, age or other comorbilities, even though mean values were always higher in those suffering metabolic diseases (5.5mg/L) compared to those values from patients not suffering the same diseases (2.7mg/L).]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Periodontitis]]></kwd>
<kwd lng="es"><![CDATA[Proteína C reactiva]]></kwd>
<kwd lng="es"><![CDATA[Enfermedad cardiovascular]]></kwd>
<kwd lng="en"><![CDATA[Periodontitis]]></kwd>
<kwd lng="en"><![CDATA[C reactive protein]]></kwd>
<kwd lng="en"><![CDATA[Cardiovascular disease.]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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