<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1659-4266</journal-id>
<journal-title><![CDATA[Cuadernos de Investigación UNED]]></journal-title>
<abbrev-journal-title><![CDATA[Cuadernos de Investigación UNED]]></abbrev-journal-title>
<issn>1659-4266</issn>
<publisher>
<publisher-name><![CDATA[Universidad Estatal a Distancia de Costa Rica]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1659-42662019000300334</article-id>
<article-id pub-id-type="doi">10.22458/urj.v11i3.2627</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Comparación de dos métodos cromatográficos para determinar clorotalonil en un fungicida comercial]]></article-title>
<article-title xml:lang="en"><![CDATA[Comparison between two chromatographic methods to determine chlorothalonil in a commercial fungicide]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Pérez López]]></surname>
<given-names><![CDATA[Esteban]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rodríguez Rodríguez]]></surname>
<given-names><![CDATA[Rosa Angélica]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de Costa Rica  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Costa Rica</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>12</month>
<year>2019</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>12</month>
<year>2019</year>
</pub-date>
<volume>11</volume>
<numero>3</numero>
<fpage>334</fpage>
<lpage>344</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_arttext&amp;pid=S1659-42662019000300334&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_abstract&amp;pid=S1659-42662019000300334&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_pdf&amp;pid=S1659-42662019000300334&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen Introducción: El clorotalonil se puede determinar por varias técnicas de análisis, entre ellas la cromatografía de gases (GC) y cromatografía líquida de alta resolución (HPLC). Estas dos técnicas son las de mayor uso en los laboratorios Objetivo: Comparar la eficacia de las metodologías analíticas por GC y por HPLC para la determinación de clorotalonil en un fungicida comercial. Métodos: Aplicamos ambos métodos a muestras equivalentes y comparamos los resultados con pruebas estadísticas. Resultados: Ambos métodos arrojaron resultados estadísticamente equivalentes y confiables. Estos parámetros fueron satisfactorios: selectividad, ámbito de trabajo y linealidad, límite de detección y cuantificación, repetibilidad, precisión intermedia, robustez, veracidad y sesgo; los consideramos lineales, precisos y exactos que cumplen con las normas del Ente Costarricense de Acreditación (ECA). Conclusiones: Ambos métodos para determinación de clorotalonil se pueden utilizar de manera confiable bajo las condiciones definidas.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract &#8220;Comparison between two chromatographic methods to determine chlorothalonil in a commercial fungicide&#8221;. Introduction: Chlorothalonil can be determined by several analytical techniques, including gas chromatography (GC) and high performance liquid chromatography (HPLC). These two techniques are used often because they have a higher level of stability and sensitivity. Objective: To compare the efficacy of analytical methodologies by GC and by HPLC for the determination of chlorothalonil in a commercial fungicide. Methods: Both the HPLC method and the GC method used by the laboratory were applied to equivalent samples and the results were compared with paired statistical tests. Results: Both methods produced statistically equivalent and reliable results. These parameters were satisfactory: selectivity, range of work and linearity, limit of detection and quantification, repeatability, intermediate precision, robustness, veracity and bias; we consider them linear, precise and exact methods that meet the norms of the Costa Rican Accreditation Entity (ECA). Conclusions: Both methods for determining chlorothalonil can be used reliably under the defined conditions.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[Agrochemicals]]></kwd>
<kwd lng="en"><![CDATA[chlorothalonil]]></kwd>
<kwd lng="en"><![CDATA[pesticides]]></kwd>
<kwd lng="en"><![CDATA[analytical method]]></kwd>
<kwd lng="en"><![CDATA[validation]]></kwd>
<kwd lng="es"><![CDATA[Agroquímicos]]></kwd>
<kwd lng="es"><![CDATA[clorotalonil]]></kwd>
<kwd lng="es"><![CDATA[plaguicidas]]></kwd>
<kwd lng="es"><![CDATA[método analítico]]></kwd>
<kwd lng="es"><![CDATA[validación]]></kwd>
</kwd-group>
</article-meta>
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