<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1409-4142</journal-id>
<journal-title><![CDATA[Revista Costarricense de Cardiología]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. costarric. cardiol]]></abbrev-journal-title>
<issn>1409-4142</issn>
<publisher>
<publisher-name><![CDATA[Asociación Costarricense de Cardiología]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1409-41422018000200016</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Disautonomía y enfermedad de chagas]]></article-title>
<article-title xml:lang="en"><![CDATA[Dysautonomia and Chagasdisease]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gutiérrez Sotelo]]></surname>
<given-names><![CDATA[Oswaldo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de Costa Rica Universidad de Ciencias Médicas ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Costa Rica</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>10</month>
<year>2018</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>10</month>
<year>2018</year>
</pub-date>
<volume>20</volume>
<fpage>16</fpage>
<lpage>18</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_arttext&amp;pid=S1409-41422018000200016&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_abstract&amp;pid=S1409-41422018000200016&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_pdf&amp;pid=S1409-41422018000200016&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen El &#8220;síndrome disautonómico&#8221; es un componente importante de la miocardiopatía chagásica. Se presenta una breve revision de su patogenia, en la cual interviene la interacción directa del parásito, inflamación y autoinmunidad, determinadas a su vez por la genética del parásito y del huésped; así como de sus principales manifestaciones clínicas.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract Dysautonomia and Chagas disease The &#8220;dysautonomic syndrome&#8221; is an important component of chagasic myocardiopathy. A brief review of its pathogenesis is presented, which involves the direct interaction of the parasite, inflammation and autoimmunity, determined in turn by the genetics of the parasite and the host; as well as its main clinical manifestations.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[enfermedad de Chagas]]></kwd>
<kwd lng="es"><![CDATA[sistema nervioso autónomo]]></kwd>
<kwd lng="es"><![CDATA[neuropatía autonómica]]></kwd>
<kwd lng="en"><![CDATA[Chagas disease - Autonimic nervous system - autonomic neuropathy]]></kwd>
</kwd-group>
</article-meta>
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