<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1409-0015</journal-id>
<journal-title><![CDATA[Medicina Legal de Costa Rica]]></journal-title>
<abbrev-journal-title><![CDATA[Med. leg. Costa Rica]]></abbrev-journal-title>
<issn>1409-0015</issn>
<publisher>
<publisher-name><![CDATA[Asociación Costarricense de Medicina Forense]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1409-00152017000100226</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Aborto recurrente]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ávila Darcia]]></surname>
<given-names><![CDATA[Sergio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gutiérrez Gómez]]></surname>
<given-names><![CDATA[Jader]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Caja Costarricense del Seguro Social Área de Salud Horquetas ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<aff id="Af2">
<institution><![CDATA[,Caja Costarricense del Seguro Social Hospital San Rafael de Alajuela ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>03</month>
<year>2017</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>03</month>
<year>2017</year>
</pub-date>
<volume>34</volume>
<numero>1</numero>
<fpage>226</fpage>
<lpage>236</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_arttext&amp;pid=S1409-00152017000100226&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_abstract&amp;pid=S1409-00152017000100226&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_pdf&amp;pid=S1409-00152017000100226&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen Los seres humanos sufren de una elevada tasa de pérdidas gestacionales después de la concepción, alcanzando cifras de 10 a 15% de todos los embarazos clínicamente reconocidos. La alta carga psicológica y frustración es común en aquellas parejas que experimentan un aborto y más aún en aquellas que presentan pérdidas gestacionales de manera recurrente. El aborto recurrente no tiene una definición clara, y se describe como la presencia de 2 o 3 abortos consecutivos antes de la semana 20 de acuerdo a las corrientes americanas y europeas, respectivamente. Se presenta en un 1 a 5% de las parejas que intentan concebir según la definición que se utilice. Esta entidad ocurre en su mayoría por causas genéticas, las cuales se ven influenciadas por la edad materna avanzada. Sin embargo, es un desorden multifactorial en el que pueden jugar un papel no solo factores genéticos sino también anatómicos, trombofilia, endocrinológicos, inmunológicos, infecciosos y de estilo de vida. Aun así, y a pesar de una evaluación exhaustiva no se logra identificar una causa subyacente hasta en un 50% de los casos.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract Human beings suffer elevated pregnancy failure rates after conception, reaching 10 to 15% of all clinically recognized pregnancies. The high psychological burden and frustration is common among couples who experience a miscarriage and moreover in those who present with recurrent pregnancy loss. This entity doesn&#8217;t have a clear definition, and it is described as the loss of 2 or 3 consecutive pregnancies before 20 weeks of gestation according to the American and European currents, respectively. It presents in 1 to 5% of couples who try to conceive depending on the definition used. Recurrent pregnancy loss majorly results from genetic causes which are greatly influenced by advanced maternal age. However, this is a multifactorial disorder in which not only genetic factors may play a role but anatomic, thrombophilia, endocrinologic, immunologic, infectious, and life style factors as well. Even after an exhaustive evaluation the underlying cause remains undetermined in up to 50% of cases.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Aborto]]></kwd>
<kwd lng="es"><![CDATA[pérdida gestacional recurrente]]></kwd>
<kwd lng="es"><![CDATA[tasa de nacidos vivos]]></kwd>
<kwd lng="es"><![CDATA[embarazo]]></kwd>
<kwd lng="es"><![CDATA[reproducción]]></kwd>
<kwd lng="en"><![CDATA[Miscarriage]]></kwd>
<kwd lng="en"><![CDATA[recurrent pregnancy loss]]></kwd>
<kwd lng="en"><![CDATA[live births rate]]></kwd>
<kwd lng="en"><![CDATA[pregnancy]]></kwd>
<kwd lng="en"><![CDATA[reproduction]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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