<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1409-0015</journal-id>
<journal-title><![CDATA[Medicina Legal de Costa Rica]]></journal-title>
<abbrev-journal-title><![CDATA[Med. leg. Costa Rica]]></abbrev-journal-title>
<issn>1409-0015</issn>
<publisher>
<publisher-name><![CDATA[Asociación Costarricense de Medicina Forense]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1409-00152016000100228</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Ejercicio como tratamiento anti-inflamatorio]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Abarca]]></surname>
<given-names><![CDATA[Alejandro]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,alejandroabarca@gmail.com  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>03</month>
<year>2016</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>03</month>
<year>2016</year>
</pub-date>
<volume>33</volume>
<numero>1</numero>
<fpage>228</fpage>
<lpage>233</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_arttext&amp;pid=S1409-00152016000100228&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_abstract&amp;pid=S1409-00152016000100228&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_pdf&amp;pid=S1409-00152016000100228&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen: Durante las últimas dos décadas, avances en investigación han revelado el potencial del ejercicio como terapia para enfermedades inflamatorias. Uno de los avances más importantes fue el descubrimiento de sistema de comunicación muscular con otros órganos y tejidos mediante la secreción de proteínas conocidas como mioquinas. Algunas de estas mioquinas, por diferentes mecanismos, inducen respuestas anti-inflamatorias con cada sesión de ejercicio, además de mejorías a largo plazo en factores de riesgo cardiovascular, obteniendo un efecto antiinflamatorio indirecto. Por lo tanto, contrario a la creencia que la actividad física podría agravar los mecanismos inflamatorios, hoy en día se considera al ejercicio como potencial tratamiento para enfermedades inflamatorias.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract: During the past two decades, advances in research have revealed the role of exercise as a therapy for inflammatory diseases. One of the most important of these advances is the discovery that skeletal muscle communicates with other organs and tissues by secreting proteins called myokines. Some myokines, by different mechanisns, induce anti-inflammatory responses with each bout of exercise and mediate long-term exercise-induced improvements in cardiovascular risk factors, having an indirect anti-inflammatory effect. Therefore, contrary to fears that physical activity might aggravate inflammatory pathways, exercise is now believed to be a potential treatment for patients with inflammatory diseases.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Inflamación sistémica persistente]]></kwd>
<kwd lng="es"><![CDATA[mioquinas]]></kwd>
<kwd lng="en"><![CDATA[Persistent systemic inflammation]]></kwd>
<kwd lng="en"><![CDATA[myokines]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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