<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1409-0015</journal-id>
<journal-title><![CDATA[Medicina Legal de Costa Rica]]></journal-title>
<abbrev-journal-title><![CDATA[Med. leg. Costa Rica]]></abbrev-journal-title>
<issn>1409-0015</issn>
<publisher>
<publisher-name><![CDATA[Asociación Costarricense de Medicina Forense]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1409-00152016000100182</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[El ácido úrico: de la gota y otros males]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Carvajal Carvajal]]></surname>
<given-names><![CDATA[Carlos]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital de Guápiles  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>03</month>
<year>2016</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>03</month>
<year>2016</year>
</pub-date>
<volume>33</volume>
<numero>1</numero>
<fpage>182</fpage>
<lpage>189</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_arttext&amp;pid=S1409-00152016000100182&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_abstract&amp;pid=S1409-00152016000100182&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_pdf&amp;pid=S1409-00152016000100182&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen: El ácido úrico es un producto de desecho del catabolismo de las purinas en humanos y es excretado por la orina. Recientemente ha habido un renovado interés en la hiperuricemia y su asociación con un número de desórdenes clínicos además de la gota, incluyendo la preeclampsia, la enfermedad renal crónica, la hipertensión, y los eventos cardiovasculares. Adicionalmente los niveles sanguíneos elevados de ácido úrico se asocian al desarrollo del síndrome metabólico. La hiperuricemia parece tener un papel dual como factor de riesgo en estas enfermedades y como condición patológica.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract: Uric acid is a waste product of purine catabolism in humans, and is excreted in urine. In recent years there has been a renewed interest in hyperuricemia and its association with a number of clinical disorders other than gout, including preeclampsia, chronic kidney disease, hypertension and cardiovascular events. Also high levels of blood uric acid have been associated with the development of metabolic syndrome. Hyperuricemia might play a double role as a risk factor for these diseases and as a pathological condition.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Hiperuricemia]]></kwd>
<kwd lng="es"><![CDATA[preclampsia]]></kwd>
<kwd lng="es"><![CDATA[gota]]></kwd>
<kwd lng="en"><![CDATA[Hyperuricemia]]></kwd>
<kwd lng="en"><![CDATA[preeclampsia]]></kwd>
<kwd lng="en"><![CDATA[gout.]]></kwd>
</kwd-group>
</article-meta>
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