<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0034-7744</journal-id>
<journal-title><![CDATA[Revista de Biología Tropical]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. biol. trop]]></abbrev-journal-title>
<issn>0034-7744</issn>
<publisher>
<publisher-name><![CDATA[Universidad de Costa Rica]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0034-77442019000200159</article-id>
<article-id pub-id-type="doi">10.15517/rbt.v67i2supl.37222</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Angiostrongylus costaricensis, un parásito neotropical cuyo diagnóstico y tratamiento siguen siendo controversiales]]></article-title>
<article-title xml:lang="en"><![CDATA[Angiostrongylus costaricensis, a neotropical parasite with a controversial diagnosis and treatment]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gutiérrez-Espeleta]]></surname>
<given-names><![CDATA[Gustavo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Páez]]></surname>
<given-names><![CDATA[Rolando]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Arias-Echandi]]></surname>
<given-names><![CDATA[María Laura]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de Costa Rica  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Costa Rica</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Caja Costarricense de Seguro Social  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<aff id="Af3">
<institution><![CDATA[,Universidad de Costa Rica  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Costa Rica</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>04</month>
<year>2019</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>04</month>
<year>2019</year>
</pub-date>
<volume>67</volume>
<numero>2</numero>
<fpage>159</fpage>
<lpage>163</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_arttext&amp;pid=S0034-77442019000200159&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_abstract&amp;pid=S0034-77442019000200159&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_pdf&amp;pid=S0034-77442019000200159&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen La angiostrongilosis abdominal es una parasitosis esporádica, que ocurre en países del neotrópico, especialmente en Costa Rica. Es una enfermedad cuyo diagnóstico es infrecuente y su tratamiento controversial. Se presenta un caso de un adulto que muestra un malestar generalizado, dolor abdominal y una intensa eosinofilia que lleva a la detección de una masa en la fosa iliaca inferior derecha. El diagnóstico definitivo se hace mediante la prueba de Morera y el tratamiento incluye el uso de azitromicina y metronidazol, no obstante no se usan antihelmínticos ni se realiza cirugía. El caso descrito pone de manifiesto que tanto el diagnóstico como el tratamiento de esta enfermedad parasitaria continúan siendo inciertos. No se descarta que exista un subregistro importante de esta parasitosis o que los síntomas sean confundidos con otras patologías.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract Abdominal angiostrogyliasis is a sporadic parasitosis that occurs in Neotropical countries, mainly in Costa Rica. It is a disease with an infrequent diagnosis and a controversial treatment. We discuss a case of an adult that presents a severe generalized discomfort, abdominal pain and an intense eosinophilia that leads to the detection of a mass at the right lower quadrant. Definitive diagnosis is achieved by the Morera Test and the treatment includes the use of azythromicin and metronidazole: no antihelmintic drugs or surgery were used. The case shows that both the diagnosis and treatment of this parasitosis are uncertain. An important underreporting of the disease may occur, as well as confusion of the symptoms with other pathologies.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[Angiostrongylus costaricensis]]></kwd>
<kwd lng="en"><![CDATA[diagnostis]]></kwd>
<kwd lng="en"><![CDATA[treatment]]></kwd>
<kwd lng="es"><![CDATA[Angiostrongylus costaricensis]]></kwd>
<kwd lng="es"><![CDATA[diagnóstico]]></kwd>
<kwd lng="es"><![CDATA[tratamiento]]></kwd>
</kwd-group>
</article-meta>
</front><back>
<ref-list>
<ref id="B1">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Araya]]></surname>
<given-names><![CDATA[A.]]></given-names>
</name>
<name>
<surname><![CDATA[Quesada]]></surname>
<given-names><![CDATA[L.]]></given-names>
</name>
<name>
<surname><![CDATA[Vargas]]></surname>
<given-names><![CDATA[H.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Angiostrongilosis abdominal]]></article-title>
<source><![CDATA[Revista Médica Costa Rica y Centro América]]></source>
<year>2015</year>
<volume>LXXI</volume>
<page-range>711-8</page-range></nlm-citation>
</ref>
<ref id="B2">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Arroyo]]></surname>
<given-names><![CDATA[R.]]></given-names>
</name>
<name>
<surname><![CDATA[Morera]]></surname>
<given-names><![CDATA[P.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Viability of the first stage larvae of Angiostrongylus costaricensis in rat feces]]></article-title>
<source><![CDATA[Journal of Parasitology]]></source>
<year>1978</year>
<volume>64</volume>
<numero>1</numero>
<issue>1</issue>
<page-range>146</page-range></nlm-citation>
</ref>
<ref id="B3">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Bonetti]]></surname>
<given-names><![CDATA[V. C.]]></given-names>
</name>
<name>
<surname><![CDATA[Graeff-Teixeira]]></surname>
<given-names><![CDATA[C.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Angiostrongylus costaricensis and the intermediate hosts: observations on elimination of L3 in the mucus and inoculation of L1 through the tegument of mollusc]]></article-title>
<source><![CDATA[Revista Sociedade Brasileira de Medicina Tropical]]></source>
<year>1998</year>
<volume>31</volume>
<page-range>289-94</page-range></nlm-citation>
</ref>
<ref id="B4">
<nlm-citation citation-type="book">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Graeff-Teixeira]]></surname>
<given-names><![CDATA[C.]]></given-names>
</name>
<name>
<surname><![CDATA[Agostini]]></surname>
<given-names><![CDATA[A.]]></given-names>
</name>
<name>
<surname><![CDATA[Rodríguez]]></surname>
<given-names><![CDATA[R.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Angiostrongiliase abdominal]]></article-title>
<person-group person-group-type="editor">
<name>
<surname><![CDATA[Tavares]]></surname>
<given-names><![CDATA[W.]]></given-names>
</name>
</person-group>
<source><![CDATA[Rotinas de diagnótico e tratamento das doencas infecciosas e parasitárias]]></source>
<year>2007</year>
<page-range>98-101</page-range><publisher-loc><![CDATA[Sao Paulo ]]></publisher-loc>
<publisher-name><![CDATA[Atheneu]]></publisher-name>
</nlm-citation>
</ref>
<ref id="B5">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Graeff-Teixeira]]></surname>
<given-names><![CDATA[C.]]></given-names>
</name>
<name>
<surname><![CDATA[Camilo-Coura]]></surname>
<given-names><![CDATA[L.]]></given-names>
</name>
<name>
<surname><![CDATA[Lenzi]]></surname>
<given-names><![CDATA[H. L.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Abdominal angiostrongyliasis: an under-diagnosed disease]]></article-title>
<source><![CDATA[Memorias Instituto Oswaldo Cruz]]></source>
<year>1991</year>
<volume>82</volume>
<page-range>353-4</page-range></nlm-citation>
</ref>
<ref id="B6">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Graeff-Teixeira]]></surname>
<given-names><![CDATA[C.]]></given-names>
</name>
<name>
<surname><![CDATA[Camillo-Coura]]></surname>
<given-names><![CDATA[L.]]></given-names>
</name>
<name>
<surname><![CDATA[Lenzi]]></surname>
<given-names><![CDATA[H. L.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Clinical and epidemiological aspects of abdominal angiostrongyliasis in southern Brazil]]></article-title>
<source><![CDATA[Revista Instituto Medicina Tropical de Sao Paulo]]></source>
<year>1991</year>
<volume>33</volume>
<page-range>373-8</page-range></nlm-citation>
</ref>
<ref id="B7">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Incani]]></surname>
<given-names><![CDATA[R. N.]]></given-names>
</name>
<name>
<surname><![CDATA[Caleiras]]></surname>
<given-names><![CDATA[E.]]></given-names>
</name>
<name>
<surname><![CDATA[Martín]]></surname>
<given-names><![CDATA[M.]]></given-names>
</name>
<name>
<surname><![CDATA[González]]></surname>
<given-names><![CDATA[C.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Human infection by Angiostrongylus costaricensis in Venezuela: first report of a confirmed case]]></article-title>
<source><![CDATA[Revista Instituto Medicina Tropical de Sao Paulo]]></source>
<year>2007</year>
<volume>49</volume>
<page-range>197-200</page-range></nlm-citation>
</ref>
<ref id="B8">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Kramer]]></surname>
<given-names><![CDATA[M. H.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[First reported outbreak of abdominal angiostrongyliasis]]></article-title>
<source><![CDATA[Clinical Infectious Diseases]]></source>
<year>1998</year>
<volume>26</volume>
<page-range>365-72</page-range></nlm-citation>
</ref>
<ref id="B9">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Loría-Cortés]]></surname>
<given-names><![CDATA[R.]]></given-names>
</name>
<name>
<surname><![CDATA[Lobo-Sanahuja]]></surname>
<given-names><![CDATA[J.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Clinical abdominal angiostrongyliasis. A study of 116 children with intestinal eosinophilic granuloma caused by Angiostrongylus costaricensis]]></article-title>
<source><![CDATA[American Journal of Tropical Medicine and Hygiene]]></source>
<year>1980</year>
<volume>29</volume>
<page-range>538-44</page-range></nlm-citation>
</ref>
<ref id="B10">
<nlm-citation citation-type="book">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Mesén]]></surname>
<given-names><![CDATA[P.]]></given-names>
</name>
<name>
<surname><![CDATA[Calvo]]></surname>
<given-names><![CDATA[N.]]></given-names>
</name>
</person-group>
<source><![CDATA[Diagnóstico de la angiostrongilosis abdominal en Costa Rica]]></source>
<year>2010</year>
<publisher-loc><![CDATA[Costa Rica ]]></publisher-loc>
<publisher-name><![CDATA[CNRP-INCIENSA]]></publisher-name>
</nlm-citation>
</ref>
<ref id="B11">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Monge]]></surname>
<given-names><![CDATA[E.]]></given-names>
</name>
<name>
<surname><![CDATA[Arroyo]]></surname>
<given-names><![CDATA[R.]]></given-names>
</name>
<name>
<surname><![CDATA[Solano]]></surname>
<given-names><![CDATA[E.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[A new definitive natural host of Angiostrongylus costaricensis]]></article-title>
<source><![CDATA[Journal of Parasitology]]></source>
<year>1978</year>
<volume>64</volume>
<numero>1</numero>
<issue>1</issue>
<page-range>34</page-range></nlm-citation>
</ref>
<ref id="B12">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Morera]]></surname>
<given-names><![CDATA[P.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Investigación del huésped definitivo de Angiostrongylus costaricensis Morera y Céspedes 1971]]></article-title>
<source><![CDATA[Boletín Chileno de Parasitología]]></source>
<year>1970</year>
<volume>25</volume>
<page-range>133-4</page-range></nlm-citation>
</ref>
<ref id="B13">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Morera]]></surname>
<given-names><![CDATA[P.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Abdominal angiostrongyliasis]]></article-title>
<source><![CDATA[Baillere&#8217;s Clinical Tropical Medicine and Communicable Diseases]]></source>
<year>1987</year>
<volume>2</volume>
<page-range>747-53</page-range></nlm-citation>
</ref>
<ref id="B14">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Morera]]></surname>
<given-names><![CDATA[P.]]></given-names>
</name>
<name>
<surname><![CDATA[Bontempo]]></surname>
<given-names><![CDATA[I.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Acción de algunos antihelmínticos sobre Angiostrongylus costaricensis]]></article-title>
<source><![CDATA[Revista Médica Hospital Nacional de Niños]]></source>
<year>1985</year>
<volume>20</volume>
<page-range>165-74</page-range></nlm-citation>
</ref>
<ref id="B15">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Morera]]></surname>
<given-names><![CDATA[P.]]></given-names>
</name>
<name>
<surname><![CDATA[Céspedes]]></surname>
<given-names><![CDATA[R.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Angiostrongylus costaricensis n. Sp (Nematoda: Metastrongyloidea), a new lungworm occurring in man in Costa Rica]]></article-title>
<source><![CDATA[Revista Biología Tropical]]></source>
<year>1971</year>
<volume>18</volume>
<numero>1-2</numero>
<issue>1-2</issue>
<page-range>173-85</page-range></nlm-citation>
</ref>
<ref id="B16">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Morera]]></surname>
<given-names><![CDATA[P.]]></given-names>
</name>
<name>
<surname><![CDATA[Pérez]]></surname>
<given-names><![CDATA[F.]]></given-names>
</name>
<name>
<surname><![CDATA[Mora]]></surname>
<given-names><![CDATA[F.]]></given-names>
</name>
<name>
<surname><![CDATA[Castro]]></surname>
<given-names><![CDATA[L.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Visceral larva migrans-like síndrome caused by Angiostrongylus costaricensis]]></article-title>
<source><![CDATA[American Journal of Tropical Medicine and Hygiene]]></source>
<year>1982</year>
<volume>31</volume>
<page-range>67-70</page-range></nlm-citation>
</ref>
<ref id="B17">
<nlm-citation citation-type="book">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Pizarro-Porras]]></surname>
<given-names><![CDATA[J.]]></given-names>
</name>
</person-group>
<source><![CDATA[Angiostrongiliasis abdominal. Revisión de 33 casos]]></source>
<year>2003</year>
<publisher-name><![CDATA[Universidad de Costa Rica]]></publisher-name>
</nlm-citation>
</ref>
<ref id="B18">
<nlm-citation citation-type="book">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Rodríguez]]></surname>
<given-names><![CDATA[R.]]></given-names>
</name>
</person-group>
<source><![CDATA[Anatomía patológica de angiostrongilose abdominal (Disertación de Maestado)]]></source>
<year>1997</year>
<publisher-loc><![CDATA[Brasil ]]></publisher-loc>
<publisher-name><![CDATA[Universidade Federal Fluminense]]></publisher-name>
</nlm-citation>
</ref>
<ref id="B19">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Rodríguez]]></surname>
<given-names><![CDATA[R.]]></given-names>
</name>
<name>
<surname><![CDATA[Martins]]></surname>
<given-names><![CDATA[R.]]></given-names>
</name>
<name>
<surname><![CDATA[Peruzzo]]></surname>
<given-names><![CDATA[L.]]></given-names>
</name>
<name>
<surname><![CDATA[Moacir]]></surname>
<given-names><![CDATA[P.]]></given-names>
</name>
<name>
<surname><![CDATA[Garcia]]></surname>
<given-names><![CDATA[E.]]></given-names>
</name>
<name>
<surname><![CDATA[Fornari]]></surname>
<given-names><![CDATA[F.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Abdominal angiostrongyliasis: report of two cases with different clinical presentations]]></article-title>
<source><![CDATA[Revista Instituto Medicina Tropical de Sao Paulo]]></source>
<year>2008</year>
<volume>50</volume>
<page-range>339-41</page-range></nlm-citation>
</ref>
<ref id="B20">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Romero-Alegría]]></surname>
<given-names><![CDATA[A.]]></given-names>
</name>
<name>
<surname><![CDATA[Belhassen-García]]></surname>
<given-names><![CDATA[M.]]></given-names>
</name>
<name>
<surname><![CDATA[Velasco-Tirado]]></surname>
<given-names><![CDATA[V.]]></given-names>
</name>
<name>
<surname><![CDATA[García-Mingo]]></surname>
<given-names><![CDATA[A.]]></given-names>
</name>
<name>
<surname><![CDATA[Alvela-Suárez]]></surname>
<given-names><![CDATA[L.]]></given-names>
</name>
<name>
<surname><![CDATA[Pardo-Lledias]]></surname>
<given-names><![CDATA[J.]]></given-names>
</name>
<name>
<surname><![CDATA[Cordero]]></surname>
<given-names><![CDATA[M.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Angiostrongylus costaricensis: Systemtic review of case reports]]></article-title>
<source><![CDATA[Advances in Infectious Disease]]></source>
<year>2014</year>
<volume>4</volume>
<page-range>36-41</page-range></nlm-citation>
</ref>
<ref id="B21">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Terada]]></surname>
<given-names><![CDATA[M.]]></given-names>
</name>
<name>
<surname><![CDATA[Kino]]></surname>
<given-names><![CDATA[H.]]></given-names>
</name>
<name>
<surname><![CDATA[Akyol]]></surname>
<given-names><![CDATA[C.]]></given-names>
</name>
<name>
<surname><![CDATA[Sano]]></surname>
<given-names><![CDATA[M.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Effects of mebendazole on Angiostrongylus costaricensis in mice with special reference to the timing of treatment]]></article-title>
<source><![CDATA[Parasitic Research]]></source>
<year>1993</year>
<volume>79</volume>
<page-range>441-3</page-range></nlm-citation>
</ref>
<ref id="B22">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Vuong]]></surname>
<given-names><![CDATA[P.]]></given-names>
</name>
<name>
<surname><![CDATA[Brama]]></surname>
<given-names><![CDATA[P.]]></given-names>
</name>
<name>
<surname><![CDATA[Bonete]]></surname>
<given-names><![CDATA[R.]]></given-names>
</name>
<name>
<surname><![CDATA[Houissa-Vuong]]></surname>
<given-names><![CDATA[S.]]></given-names>
</name>
<name>
<surname><![CDATA[Catanzano-Laroudie]]></surname>
<given-names><![CDATA[M.]]></given-names>
</name>
<name>
<surname><![CDATA[Baviera]]></surname>
<given-names><![CDATA[E.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Necrotic eosinophilic angiitis with ileal perforation and peritonitis secondary to abdominal angiostrongyliasis]]></article-title>
<source><![CDATA[Presse Médicale]]></source>
<year>2002</year>
<volume>31</volume>
<page-range>1700-3</page-range></nlm-citation>
</ref>
<ref id="B23">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Wu]]></surname>
<given-names><![CDATA[S.]]></given-names>
</name>
<name>
<surname><![CDATA[French]]></surname>
<given-names><![CDATA[S.]]></given-names>
</name>
<name>
<surname><![CDATA[Turner]]></surname>
<given-names><![CDATA[J.]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Eosinophilic ileitis with perforation caused by Angiostrongylus costaricensis. A case study and review]]></article-title>
<source><![CDATA[Archives of Pathology and Laboratory Medicine]]></source>
<year>1997</year>
<volume>121</volume>
<page-range>989-91</page-range></nlm-citation>
</ref>
</ref-list>
</back>
</article>
