<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0001-6002</journal-id>
<journal-title><![CDATA[Acta Médica Costarricense]]></journal-title>
<abbrev-journal-title><![CDATA[Acta méd. costarric]]></abbrev-journal-title>
<issn>0001-6002</issn>
<publisher>
<publisher-name><![CDATA[Colegio de Médicos y Cirujanos de Costa Rica]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0001-60022021000400229</article-id>
<article-id pub-id-type="doi">10.51481/amc.v63i4.1120</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Trombocitopenia inmune asintomática asociada a COVID-19]]></article-title>
<article-title xml:lang="en"><![CDATA[Asymptomatic Inmune Thrombocytopenia associated with COVID-19]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Quintana-Quirós]]></surname>
<given-names><![CDATA[Orlando]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Valerio-Gil]]></surname>
<given-names><![CDATA[Lilem]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rodríguez-Palma]]></surname>
<given-names><![CDATA[Fabián]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Caja Costarricense de Seguro Social Centro Especializado para la Atención de pacientes COVID- 19 Servicio de Medicina interna]]></institution>
<addr-line><![CDATA[San José ]]></addr-line>
<country>Costa Rica</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Caja Costarricense de Seguro Social Centro Especializado para la Atención de pacientes COVID- 19 Servicio de Medicina interna]]></institution>
<addr-line><![CDATA[San José ]]></addr-line>
<country>Costa Rica</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Caja Costarricense de Seguro Social Centro Especializado para la Atención de pacientes COVID- 19 Servicio de Medicina interna]]></institution>
<addr-line><![CDATA[San José ]]></addr-line>
<country>Costa Rica</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>12</month>
<year>2021</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>12</month>
<year>2021</year>
</pub-date>
<volume>63</volume>
<numero>4</numero>
<fpage>229</fpage>
<lpage>234</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_arttext&amp;pid=S0001-60022021000400229&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_abstract&amp;pid=S0001-60022021000400229&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_pdf&amp;pid=S0001-60022021000400229&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen El virus SARS-CoV-2 produce una enfermedad con múltiples manifestaciones clínicas. Los hallazgos hematológicos anormales, entre ellos la trombocitopenia, han surgido como una complicación emergente de la COVID-19. A nivel mundial, se han descrito casos que asocian la infección por el virus SARS-CoV-2 con la trombocitopenia inmune; sin embargo, este es el primer registro publicado en Costa Rica a la fecha. En este reporte clínico se describe una paciente adulta mayor atendida en el Centro Especializado para la Atención de pacientes COVID-19, uno de los hospitales de la Caja Costarricense de Seguro Social. Ingresó con cuadro de COVID-19 severo que, durante su estancia hospitalaria, desarrolló plaquetopenia aguda asintomática. Posterior a la exclusión de otros diagnósticos causales de este signo clínico, se hizo diagnóstico de trombocitopenia inmune con asociación a SARS-CoV-2 Además del manejo protocolizado por la COVID-19 que incluyó dexametasona y enoxaparina, recibió un ciclo adicional de dexametasona junto con una dosis de inmunoglobulina intravenosa, tras lo cual presentó una recuperación completa del conteo plaquetario.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract The SARS-CoV-2 virus is a disease that produces multiple clinical manifestations. Abnormal hematologic findings, such as thrombocytopenia, have emerged as a complication of COVID-19. Worldwide, series of cases of association between the SARS-CoV-2 virus and immune thrombocytopenia have been described; however, reported to date, it is the first case published in Costa Rica. This clinical report describes the case of an elderly female admitted in the Centro Especializado para la Atención de pacientes COVID-19, one of the hospitals of the Caja Costarricense de Seguro Social. She was admitted with severe COVID-19, and during her hospital stay, she developed asymptomatic acute thrombocytopenia. The diagnosis of immune thrombocytopenia was made after excluding other diagnoses causing this sign. In addition of the protocolized management of COVID-19 with steroids and enoxaparin, she was treated with an additional cycle of dexamethasone and a dose of intravenous immunoglobulin. After this, she showed a complete recovery of the platelet count.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[COVID-19]]></kwd>
<kwd lng="es"><![CDATA[SARS-CoV-2]]></kwd>
<kwd lng="es"><![CDATA[Trombocitopenia]]></kwd>
<kwd lng="es"><![CDATA[Púrpura trombocitopénica]]></kwd>
<kwd lng="en"><![CDATA[COVID-19]]></kwd>
<kwd lng="en"><![CDATA[SARS-CoV-2]]></kwd>
<kwd lng="en"><![CDATA[Thrombocytopenia]]></kwd>
<kwd lng="en"><![CDATA[Thrombocytopenic purpura]]></kwd>
</kwd-group>
</article-meta>
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