<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0001-6002</journal-id>
<journal-title><![CDATA[Acta Médica Costarricense]]></journal-title>
<abbrev-journal-title><![CDATA[Acta méd. costarric]]></abbrev-journal-title>
<issn>0001-6002</issn>
<publisher>
<publisher-name><![CDATA[Colegio de Médicos y Cirujanos de Costa Rica]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0001-60022020000100007</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Resistencia a desinfectantes y su relación con la resistencia a los antibióticos]]></article-title>
<article-title xml:lang="en"><![CDATA[Resistance to disinfectants and their relationship with antibiotic resistance]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Chacón-Jiménez]]></surname>
<given-names><![CDATA[Luz]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rojas-Jiménez]]></surname>
<given-names><![CDATA[Keilor]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de Costa Rica Instituto de Investigaciones en Salud (INISA) ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Costa Rica</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad de Costa Rica Escuela de Biología ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Costa Rica</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>03</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>03</month>
<year>2020</year>
</pub-date>
<volume>62</volume>
<numero>1</numero>
<fpage>7</fpage>
<lpage>12</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_arttext&amp;pid=S0001-60022020000100007&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_abstract&amp;pid=S0001-60022020000100007&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_pdf&amp;pid=S0001-60022020000100007&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen  Objetivo:  Sistematizar los principales mecanismos de acción de los desinfectantes y describir mecanismos de resistencia comunes entre biocidas y antibióticos.  Métodos:  Se realizó una revisión bibliográfica de artículos científicos entre 2000 y julio de 2019, sobre la relación entre la resistencia a biocidas y a los antibióticos, utilizando como palabras clave &#8220;antibiotic&#8221;, &#8220;biocide&#8221;, &#8220;resistance&#8221; y &#8220;bacteria&#8221;, en las bases de datos PubMed y Google Scholar.  Conclusiones:  Existe numerosa evidencia científica que indica la relación entre bacterias resistentes a los desinfectantes y la adquisición de resistencia a los antibióticos, lo que implica un replanteamiento del uso de esas sustancias en diferentes contextos clínicos, con el fin de minimizar el impacto que puedan tener en la selección de microorganismos multirresistentes a los antibióticos.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract  Aim:  To summarize the main mechanisms of action of disinfectants and to describe some common resistance mechanisms shared between biocides and antibiotics.  Methods:  A bibliographic review of scientific articles was carried out between 2000 and July 2019 on the relationship between resistance to biocides and antibiotics, using as keywords &#8220;antibiotic&#8221;, &#8220;biocide&#8221;, &#8220;resistance&#8221; and &#8220;bacteria&#8221; in the data bases of PubMed and Google Scholar.  Conclusions:  Numerous scientific studies indicate a relationship between disinfectant-resistant bacteria and the acquisition of antibiotic resistance. It is necessary to analyze the use of these substances in the clinical context in order to minimize the impact that they may have on the selection of antibiotic-resistant microorganisms.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[bacterias]]></kwd>
<kwd lng="es"><![CDATA[desinfectantes]]></kwd>
<kwd lng="es"><![CDATA[resistencia]]></kwd>
<kwd lng="es"><![CDATA[antibióticos]]></kwd>
<kwd lng="en"><![CDATA[bacteria]]></kwd>
<kwd lng="en"><![CDATA[disinfectants]]></kwd>
<kwd lng="en"><![CDATA[antibiotic resistance.]]></kwd>
</kwd-group>
</article-meta>
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</ref>
<ref id="B52">
<label>52</label><nlm-citation citation-type="">
<collab>Universidad de Costa Rica</collab>
<source><![CDATA[Escherichia coli strain PTA_A1167-1]]></source>
<year></year>
</nlm-citation>
</ref>
</ref-list>
</back>
</article>
