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Odovtos International Journal of Dental Sciences
On-line version ISSN 2215-3411Print version ISSN 1659-1046
Abstract
ORTIZ-MAGDALENO, Mariné et al. Behavior of Mesenchymal Stem Cells Obtained From Dental Tissues: A Review of the Literature. Odovtos [online]. 2019, vol.21, n.1, pp.31-40. ISSN 2215-3411. http://dx.doi.org/10.15517/ijds.v0i0.34884.
20.
The success of tissue engineering in combination with tissue regeneration depends on the behavior and cellular activity in the biological processes developed within a structure that functions as a support, better known as scaffolds, or directly at the site of the injury. The cell-cell and cell-biomaterial interaction are key factors for the induction of a specific cell behavior, together with the bioactive factors that allow the formation of the desired tissue. Mesenchymal Stem Cells (MSC) can be isolated from the umbilical cord and bone marrow; however, the behavior of Dental Pulp Stem Cells (DPSC) has been shown to have a high potential for the formation of bone tissue, and these cells have even been able to induce the process of angiogenesis. Advances in periodontal regeneration, dentin-pulp complex, and craniofacial bone defects through the induction of MSC obtained from tooth structures in in vitro-in vivo studies have permitted the obtaining of clinical evidence of the achievements obtained to date.
Keywords : Dental pulp stem cells; Tissue engineering; Regenerative medicine; Dental tissues; Mesenchymal Stem Cells; Scaffolds.