SciELO - Scientific Electronic Library Online

 
vol.20 issue1Trajectories of frailty and related factors of elderly people in Mexico Labor force participation during COVID-19 economic crisis in Mexico: care work demands and differential recovery between men and womenChronic non-communicable diseases in Argentina: Model and forecast by sex and age author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

  • Have no similar articlesSimilars in SciELO

Share


Población y Salud en Mesoamérica

On-line version ISSN 1659-0201

Abstract

CHAVES CAMPOS*, Andrés et al. Comparative study of cytogenetic biomonitoring in veterinary personnel occupationally exposed to ionizing radiation by cytokinesis-block micronucleus assay. PSM [online]. 2022, vol.20, n.1, pp.78-98. ISSN 1659-0201.  http://dx.doi.org/10.15517/psm.v20i1.48074.

Introduction: Ionizing radiation (RI) can induce the formation of micronuclei (MN). The formation of MN is used as a biomarker of radiation-induced genetic damage. Objective: assess DNA damage resulting from occupational exposure to RI in veterinary personnel. Methodology: the cytokinesis-block micronucleus assay (MNBC) was used to compare the observed frequency of MN in 40 individuals occupationally exposed to ionizing radiation with respect to a control group of 32 participants, both groups belonging to veterinary personnel. In addition, demographic, lifestyle and occupational variables that could influence the formation of MN were recorded. Results: univariate analysis did not show significant differences in the frequency of MN between the study groups (p=0.118). Using multivariate analysis, it was found that approximately 27% (adjusted R2= 0.269) of the variability in the frequency of MN can be explained by the joint influence of age, sex and the number of radiographic images performed by the participant. Age is the variable with the greatest relative importance (β = 0.504), followed by the sex of the participant (β = -0.316) and the number of X-rays performed per day (β = 0.214). Conclusions: the frequency of MN tends to increase in women, as the participant's age increases and as the number of radiographic images performed increases.

Keywords : micronucleus assay; ionizing radiation; genotoxicity test; occupational exposure.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )