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Revista Costarricense de Cardiología

Print version ISSN 1409-4142

Abstract

NAVARRO SOLANO, Jonatan  and  POVEDA FERNANDEZ, Jonathan. El efecto de los antihiperglicemiantes en los parámetros ecocardiográficos diastólicos y sistólicos. Rev. costarric. cardiol [online]. 2020, vol.22, n.1, pp.53-59. ISSN 1409-4142.

Metabolic disease type 2 diabetes mellitus causes alterations in both structure and myocardial functionality by different biochemical mechanisms which can cause diastolic and systolic dysfunction, which is why the use of antihyperglycemic agents apart from its effect in the reduction of hyperglycemia and glycosylated hemoglobin, some groups have shown reduction in cardiovascular mortality and hospitalizations for heart failure this based on clinical studies, by hypothesis, theories and pleiotropic mechanisms on this impact on the myocardium. On the other hand, the effect of these drugs on the myocardium has also been evaluated by transthoracic echocardiography. Therefore, the aim of this article is to analyze the values of systolic and diastolic echocardiographic parameters in type 2 diabetic patients or some underlying heart disease as a history of myocardial infarction and heart failure with the use of metformin, sulfonylureas, inhibitors of the dipeptidylpeptidase 4 (sitagliptin, alogliptin and linagliptin, vildagliptin), GLP1 analogues (liraglutide, albiglutide and exenatide).

Keywords : 4 inhibitors; GLP1 analogues.

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