Abstract

MENDEZ-LOPEZ, Max; SALAZAR-SANCHEZ, Lizbeth  and  PORRAS P, Juan. Thrombophilia: Improving Diagnosis with an Evidence-Based Approach. Rev. costarric. cardiol [online]. 2013, vol.15, n.2, pp.25-30. ISSN 1409-4142.

Thromboembolic disorders are one of the leading causes of morbidity and mortality among patients hospitalized as well as outpatients. There is an active debate about the contribution of genetic causes to thrombotic events such as deep vein trombosis mainly because of the great variability between gene-gene and gene-environment interactions. Due to growing new evidence, there is a trend toward limiting thrombophilia testing to patients in whom the result could influence the treatment strategy. The only reliable method to diagnose mutations in thrombophilia is by means of molecular biology tests which incurrs in a high cost to our nacional social security. For this reasons, a revision of current literature is necessary to develop a evidence based- approach to patients with these diseases.

Keywords : Deep Vein Thrombosis; Pulmonary Embolism; Thrombophilia; Anticoagulation; Risk Factors.

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