Abstract

RIVERA, Antonio et al. DNA Depletion Byclinical Isolated Mycoplasmas, México. Rev. costarric. salud pública [online]. 2013, vol.22, n.2, pp.144-148. ISSN 1409-1429.

The limited capacity of essential biosynthetic precursors mycoplasma enabled them to develop molecular mechanisms for acquisition from their hosts. Objective: To determine the ability of DNA degradation in mycoplasma isolated from clinical samples. Methods: From clinical samples of throat and vaginal swabs mycoplasmas were isolated by microbiological method and validated by PCR. The positive samples were evaluated for their ability to degrade DNA halo formation method on agar. Results: the ability to degrade DNA from clinical isolates of mycoplasma was evident and showed a significant difference (P <0.05) compared to the reference strain. Conclusions: Mycoplasma in clinical isolates have DNase activity, implying a role for the acquisition of nucleic acid precursors, and conditioning the host cells´ alteration.

Keywords : Mycoplasmas; Pharynx; Vaginal Smears; DNA Fragmentation.

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