SciELO - Scientific Electronic Library Online

 
vol.33 issue4Wood Wide Web: communication through the mycorrhizal networkEvaluation in house mesh of the effect of four biological products for the combat of jobotos (Phyllophaga sp.) author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

  • Have no similar articlesSimilars in SciELO

Share


Revista Tecnología en Marcha

On-line version ISSN 0379-3982Print version ISSN 0379-3982

Abstract

ALFARO-ALFARO, Álvaro Esteban et al. C-phycocyanins: immune system modulation and its possible application as therapy against cancer. Tecnología en Marcha [online]. 2020, vol.33, n.4, pp.125-139. ISSN 0379-3982.  http://dx.doi.org/10.18845/tm.v33i4.4653.

Cancer is a complex, heterogeneous, and dynamic disease, characterized by uncontrolled mitosis. Historically, it has been treated with surgery, radiotherapy and chemotherapy, and immunotherapy in more recent years. For this, different proteins have been investigated for the modulation of the immune response. A group of these are C-phycocyanins, biliproteins from bluish-green microalgae such as Spirulina platensis. The anti-inflammatory environment in healthy people is a prophylactic measure to reduce the risk of developing a specific cancer type. Its intake has shown that behavior, by suppressing the release of pro-inflammatory substances. An immunomodulatory effect has also been appreciated by increasing or decreasing the expression of CD59, and causing the macrophage proliferation and the release of inflammatory substances. The latter is an indication that there is insufficient information to corroborate its use as a prophylactic or therapeutic option against cancer. Therefore, the information about natural substances such as these ones are transcendental, because although they are more attractive to treat said disease, there are no fully proven therapeutic effects.

Keywords : Cancer; immunotherapy; C-phycocyanin; immune response.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )