Serviços Personalizados
Journal
Artigo
Espanhol (pdf)
Artigo em XML
Referências do artigo
Tradução automática
Enviar este artigo por emailIndicadores
Citado por SciELO 
Acessos
Links relacionados
Similares em
SciELO
Compartilhar
Permalink
Acta Médica Costarricense
versão On-line ISSN 0001-6002versão impressa ISSN 0001-6012
Resumo
VARGAS-JIMENEZ, José e CAMPOS-NUNEZ, Christian. First-line treatment for eradication of Helicobacter pylori: Still an effective therapy. Acta méd. costarric [online]. 2023, vol.65, n.1, pp.21-25. ISSN 0001-6002. http://dx.doi.org/10.51481/amc.v65i1.1130.
Aim: The main objective of this study is to determine the response to the firstline treatment regimen with triple standard therapy (amoxicillin, clarithromycin, omeprazole), to eradicate Helicobacter pylori in a certain population. The goal is to determine if the proposed regimen in international guidelines services is still a suitable option for patients in a certain region of Costa Rica.
Methods:
The study took place in San Francisco de Asís Hospital, Grecia, Alajuela, Costa Rica. All patients with a Helicobacter pylori infection that were given first- line treatment with triple therapy (amoxicillin, clarithromycin and omeprazole) for its eradication for 14 days, in the period between February of 2017 and February of 2019, were included in the study.
Results:
A total of 369 cases were identified. The diagnosis was made with biopsy in 96.4% of patients. Response to first-line treatment was achieved in 90.5% corroborated by fecal antigen in 92.1% of all cases.
Conclusions: This study shows that triple therapy with amoxicillin, clarithromycin and omeprazole for 14 days maintains an adequate level of efficacy. However, it must be considered that these results are from a specific area and may not reflect the reality of the entire country.
Palavras-chave : Drug Resistance; Bacterial; Helicobacter pylori; Stomach Neoplasms; Helicobacter Infections; Disease Eradication.
