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Acta Médica Costarricense
versión On-line ISSN 0001-6002versión impresa ISSN 0001-6012
Resumen
SANABRIA-CALVO, María Montserrat et al. Radiotherapy in pediatric patients with acute lymphocytic leukemia: a 9-year experience. Acta méd. costarric [online]. 2022, vol.64, n.4, pp.48-54. ISSN 0001-6002.
Aim:
To describe the epidemiological and clinical characteristics of patients with acute lymphocytic leukemia, attended at the National Children´s Hospital “Dr. Carlos Sáenz Herrera” that received external radiation therapy between January 2009 and December 2017. Methods: It is an observational, descriptive study. Clinical records of pediatric patients (0-13 years) with acute lymphoblastic leukemia that received external radiotherapy in the study period were retrospectively reviewed. A descriptive statistical analysis of the qualitative and quantitative variables was applied.
Results:
58 patients were studied, 79,3% were males. The mean age was 7,3 years. 84,2% were classified as L1, 84,2% had common B immunophenotype and 56,9% were in the high risk group at diagnosis. The main indication for radiotherapy was relapse (67,7%). About half the patients received radiotherapy to central nervous system and the other half to testicles. The main side effects were cutaneous.
Conclusions:
The results obtained were comparable to those seen in literature. Radiotherapy is important in leukemia treatment, particularly in relapse and high risk patients.
Palabras clave : Radiotherapy; acute lymphocytic leukemia; pediatric; epidemiology; treatment.