Abstract

SOLANO-ORTIZ, Marcia; AVILA-DE BENEDICTIS, Lydiana  and  SOTO-QUIROS, Manuel. La relación entre el asma y la enfermedad pulmonar obstructiva crónica. Acta méd. costarric [online]. 2007, vol.49, n.1, pp.21-25. ISSN 0001-6002.

Asthma and COPD are common pulmonary diseases with similarities and differences. Recent genetic studies have given important information about multiple susceptible loci for both diseases. Studies of the genome have showed similar results in at least a chromosomal region in both diseases and demonstrate the interaction the environmental factors (for example, active smoking in the patients with COPD, or passive smoking in those with asthma). Currently there are few recent studies about airway remodelling and its importance in chronic persistent asthmatic patients, this might explain in some way the progression of these persons to chronic obstructive pulmonary diseases.

Keywords : COPD; smoking; remodeling of de airway.

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