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Acta Médica Costarricense
versión On-line ISSN 0001-6002versión impresa ISSN 0001-6012
Resumen
FIEDLER-VELASQUEZ, Eduardo; GOURZONG- TAYLOR, Charles; GOYENAGA-HERNANDEZ, Pedro y LOPEZ-CASTRO, Jairo. Enfermedad de Castleman. Reporte de 14 casos de 1990-2002 en el "Hospital Dr. Rafael Angel Calderón Guardia", dos con presentación inusual y revisión de literatura. Acta méd. costarric [online]. 2005, vol.47, n.3, pp.137-143. ISSN 0001-6002.
Castlemans disease is a rare lymphoproliferative disorder. Its etiology is unknown and its course is usually benign. It is secondary to an irregular growth of lymphatic tissue and it can exhibirt 2 forms: a localized and a disseminated or multicentric. Histopathologically there are 3 forms: hialine vascular, plasma cell and mixed or transitional. The first type usually has a benign clinical course and is characterized by adenomegalies, the plasma cell or mixed forms, however, may exhibit clinical or laboratory anomalies, such as fever, weight loss, anemia and hyperglobulinemia. The latter forms may evolve to Hodgkin lymphoma. We found 14 cases at the Calderon Guardia Hospital Pathology Department data base (1990-2002). The clinical course of 2 patients is presented
Palabras clave : Castleman¢s disease; lymphoproliferative disorder.