Abstract

SALAS-SEGURA, Donato A.; PADILLA-CUADRA, Juan I.  and  SALAS-SEGURA, Juliana. Vasculitis por Propiltiouracilo: reporte de un caso. Acta méd. costarric [online]. 2002, vol.44, n.2, pp.87-89. ISSN 0001-6002.

We report a case of 43-year-old woman who developed two complications associated with the use of propylthiouracil: vasculitis and agranulocytosis. Vasculitis associated with antithyroid therapy is a rare well-documented clinical entity with a pathogenic mechanism not clear yet. There a few published reports of an association between treatment with propylthiouracil, and the occurrence of ANCA positivity and ANCA-associated vasculitis. This is probably one more.

Keywords : Propitiouracilo; vasculitis; autoanticuerpos citoplasmáticos; anti-neutrófilo.