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Acta Médica Costarricense
versão On-line ISSN 0001-6002versão impressa ISSN 0001-6012
Resumo
RIVERA-CHAVARRIA, Ana e ESPINOZA-AGUIRRE, Azálea. Thalidomide in Costa Rica: uses, regulatory and ethical context. Acta méd. costarric [online]. 2019, vol.61, n.2, pp.73-76. ISSN 0001-6002.
In recent decades, thalidomide´s anti-inflammatory, anti-angiogenic and immunoregulatory properties have led as an alternative or second-choice therapy for various pathologies. It is currently included in the Official List of Medicines and Regulations of the Costa Rican Social Security (LOM). However, thalidomide´s resurgence and its analogues, reproductive behavior changes, assisted reproduction technology, biomedical research and medical judicialization, indicates that a review of the current indications and safety measures are necessary to prevent the most serious adverse effect: teratogenesis. In this research, we aim to summarize thalidomide´s current uses, regulatory and ethical context in Costa Rica.
Palavras-chave : Thalidomide; IMiDS; ethical issues; regulation.