Mathematics Subject Classification: 93A30, 92B99, 37N25
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Artículo
Dengue model with early-life stage of vectors and age-structure within host
Modelo de dengue con etapa temprana en vectores y estructura de edad en el huésped
1University of Costa Rica, CIMPA, School of Mathematics, San José, Costa Rica; fabio.sanchez@ucr.ac.cr
2University of Costa Rica, CIMPA, School of Mathematics, San José, Costa Rica; juan.calvo@ucr.ac.cr
We construct an epidemic model for the transmission of dengue fever with an early-life stage in the vector dynamics and age-structure within hosts. The early-life stage of the vector is modeled via a general function that supports multiple vector densities. The basic reproductive number and vector demographic threshold are computed to study the local and global stability of the infection-free state. A numerical framework is implemented and simulations are performed.
Keywords: dengue fever; epidemic models; mathematical modeling; vectorborne diseases; age-structured model.
Se construye un modelo epidémico para la dinámica de transmisión de la fiebre del dengue con etapa temprana de vida en los vectores y estructura de edad en las clases de los huéspedes. La etapa de vida temprana del vector, se modela a través de una función general que admite múltiples densidades de vectores. El número reproductivo básico y vector de umbral demográfico, se calculan para estudiar la estabilidad local y global del estado libre de infección. Se implementa además un marco numérico y se realizan simulaciones.
Palabras clave: dengue; modelos epidémicos; modelizaje matemático; enfermedades vectoriales; modelos con estructura de edad.
Mathematics Subject Classification: 93A30, 92B99, 37N25
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Acknowledgements
We thank the Research Center in Pure and Applied Mathematics and the Mathematics Department at Universidad de Costa Rica for their support during the preparation of this manuscript. The authors gratefully acknowledge institutional support for project B8747 from an UCREA grant from the Vice Rectory for Research at Universidad de Costa Rica.
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Recibido: 07 de Agosto de 2019; Revisado: 26 de Agosto de 2019; Aprobado: 18 de Septiembre de 2019